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Novel Method for the Preparation of Enantiomerically Pure Propargylic Substituted Compounds

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NIAID Data Ecosystem2026-03-06 收录
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We have found a novel method for the preparation of enantiomerically pure propargylic alkylated compounds from an achiral propargylic alcohol assisted by a ruthenium complex bearing BINAP as a chiral ligand. It is noteworthy that products bearing completely opposite configurations are obtained with an almost 100% ee.

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2016-05-05
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