Tandem Synthesis of 3‑Halo-5-Substituted Isoxazoles from 1‑Copper(I) Alkynes and Dihaloformaldoximes
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A tandem synthesis of 3-halo-5-substituted isoxazoles has been developed from 1-copper(I) alkynes and dihaloformaldoximes under base-free conditions. Thus, 1,3-dipolar cycloaddition and all its drawbacks can now be avoided completely.
创建时间：
2016-02-16
