首页/数据集/Inhibition of protein arginine methyltransferase 6 (PRMT6) activates interferon signaling and induces apoptosis in endometrial cancer cells via histone modification

Inhibition of protein arginine methyltransferase 6 (PRMT6) activates interferon signaling and induces apoptosis in endometrial cancer cells via histone modification

NIAID Data Ecosystem2026-05-01 收录

子宫内膜癌表观遗传机制

PRMT6

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE239296 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2024-02-08

肝细胞癌基因

PRMT6

Systematic identification of altered genes downstream of PRMT6. Platform used - Agilent SurePrint G3 Human Gene Expression v3 8x60K microarray kit. BEL7402 cells were transduced with lentivirus contai

NIAID Data Ecosystem20

Protein arginine methyltransferase 6 drives endocrine resistance in breast cancer: ERα and NFkB signalling directly regulate PRMT6 expression

乳腺癌耐药性

PRMT6

Gain- and Loss-of-function coupled with RNA-seq revealed that PRMT6 is involved in pathways drives breast carcinogenesis. Mammary specific PRMT6 mice and PRMT6 knockdowned MCF-7 and MDA-231 cells were

NIAID Data Ecosystem10

A First-in-Class, Highly Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 6

PRMT6

表观遗传学药物发现

Protein arginine methyltransferase 6 (PRMT6) catalyzes monomethylation and asymmetric dimethylation of arginine residues in various proteins, plays important roles in biological processes, and is asso

Figshare2021-02-16 更新00

Inhibition of protein arginine methyltransferase 6 (PRMT6) activates interferon signaling and induces apoptosis in endometrial cancer cells via histone modification [ChIP-seq]. Inhibition of protein arginine methyltransferase 6 (PRMT6) activates interferon signaling and induces apoptosis in endometrial cancer cells via histone modification [ChIP-seq]

子宫内膜癌表观遗传学

PRMT6

Histone modification, a major epigenetic mechanism which regulates gene expression by chromatin remodeling, introduces dynamic changes in chromatin architecture. Protein arginine methyltransferase 6 (

NIAID Data Ecosystem10

Discovery of a First-in-Class Protein Arginine Methyltransferase 6 (PRMT6) Covalent Inhibitor

PRMT6

癌症靶向治疗

Protein arginine methyltransferase 6 (PRMT6) plays important roles in several biological processes associated with multiple cancers. Well-characterized potent, selective, and cell-active PRMT6 inhibit

Figshare2020-05-05 更新00

Inhibition of protein arginine methyltransferase 6 (PRMT6) activates interferon signaling and induces apoptosis in endometrial cancer cells via histone modification

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