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Dimethyl Sulfide Induced [3 + 2] Annulation Strategy: An Efficient Synthesis of Functionalized Dihydropyrazole Derivatives Using the Baylis−Hillman Bromides

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NIAID Data Ecosystem2026-03-06 收录
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Baylis−Hillman bromides have been successfully employed as a valuable source of 1,3-dipoles for cycloaddition onto dialkyl azodicarboxylates (dipolarophiles) under the influence of dimethyl sulfide and potassium carbonate to provide functionalized dihydropyrazole derivatives in a simple one-pot [3 + 2] annulation strategy.

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2016-02-27
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