Structure-Based Discovery and Optimization of Furo[3,2-c]pyridin-4(5H)-one Derivatives as Potent, Second Bromodomain (BD2)-Selective Inhibitors of BRD4

科学数据银行2022-03-07 更新2026-04-23 收录

BRD4BD2选择性抑制剂

基于结构的药物设计

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https://www.scidb.cn/en/detail?dataSetId=7221e3a325064e579e40f9f158f8bb50 数据链接链接失效反馈

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资源简介：

This zip package includes all the raw data involving in the article "Structure-Based Discovery and Optimization of Furo[3,2-c]pyridin-4(5H)-one Derivatives as Potent, Second Bromodomain (BD2)-Selective Inhibitors of BRD4"submitted to the journal of the Journal of Medicinal Chemistry.

提供机构：

Jibu Lu; Maofeng Zhang; Yulai Zhou; Center for Chemical Biology and Drug Discovery, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, No. 190 Kaiyuan Avenue, Guangzhou, 510530, China; Hongrui Xu; Jinsong Liu; Xiaoshan Chen; School of Biological Sciences & Maurice Wilkins Centre, University of Auckland, Auckland 1010, New Zealand; Ruibo Dong; Center for Chemical Biology and Drug Discovery, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, No. 190 Kaiyuan Avenue, Guangzhou, 510530, China;Guangdong Provincial Key Laboratory of Biocomputing, Joint School of Life Sciences, Guangzhou Institutes of Biomedicine and Health, Guangzhou Medical University, Chinese Academy of Sciences, Guangzhou 510530, China;China-New Zealand Joint Laboratory on Biomedicine and Health, Guangzhou, 510530, China;State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China; Center

创建时间：

2022-03-07