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Distinct tissue-niche localization and function of synovial tissue myeloid DC subsets in health, and in active and remission Rheumatoid Arthritis

NIAID Data Ecosystem2026-05-02 收录

类风湿性关节炎微环境

树突状细胞组织定位

数据链接：

https://www.omicsdi.org/dataset/bioimages/S-BIAD1388 数据链接链接失效反馈

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资源简介：

immunofluorescent staining in Synovial tissue of Healthy, active Rheumatoid arthritis and and Rheumatoid arthritis in remission.

应用场景：

创建时间：

2024-12-02

类风湿性关节炎微环境

树突状细胞-Treg相互作用

A) Influx of FoxP3+ cells (red nuclear stain) in mouse synovial tissue at day 28 (2). Morphological picture of synovial tissue (1) were marked area indicates site of FoxP3 staining (2), and negative c

NIAID Data Ecosystem20

Quantification of PD-L1, PD1 and CD3 staining in treatment-naïve early RA synovial tissue biopsies.

类风湿性关节炎微环境

免疫检查点分子表达

Table shows PD-L1+ at different degree, including <1%, ≥1% or ≥50%; The percentage of CD3+ and PD1+ cells as a proportion of total synovial infiltrating immune cells for each section is also presented

NIAID Data Ecosystem20

Single-cell RNA-seq of CD8 T cells sorted from one sample of seropositive rheumatoid arthritis synovial fluid. Single-cell RNA-seq of CD8 T cells sorted from one sample of seropositive rheumatoid arthritis synovial fluid

单细胞免疫组学

类风湿性关节炎微环境

We used FACS to sort CD8 T cells from synovial fluid mononuclear cells from one patient with seropositive rheumatoid arthritis Overall design: SFMCs were thawed, stained with MR1 tetramers and surface

NIAID Data Ecosystem10

Raw IMC images associated with De Lima et al. 2023, BioRxiv

空间蛋白质组学

类风湿性关节炎微环境

This dataset contains the raw IMC images associated with the paper "Spatial mapping of rheumatoid arthritis synovial niches reveals specific macrophage networks associated with response to therapy" (D

NIAID Data Ecosystem20

Single-cell, paired heavy- and light-chain immunoglobulin sequencing of B cells from peripheral blood and synovial tissue of rheumatoid arthritis subjects

B细胞受体库分析

类风湿性关节炎微环境

In this study, we investigated the B cell repertoire present in peripheral blood and synovial tissue from subjects with established rheumatoid arthritis. The paired heavy- and light-chain immunoglobul

NIAID Data Ecosystem10

Distinct tissue-niche localization and function of synovial tissue myeloid DC subsets in health, and in active and remission Rheumatoid Arthritis

资源简介：

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