Comparative efficacy and safety of oral H1-antihistamines in seasonal and perennial allergic rhinitis: source-of-truth repository v3.0

Complete clean source-of-truth repository for a systematic review and endpoint-specific Bayesian network meta-analysis of selected oral H1-antihistamines in seasonal allergic rhinitis (SAR) and perennial/persistent allergic rhinitis (PAR). This v3.0 repository release integrates the v2.0 analytic lock, locked arm-level analytic datasets, R/JAGS code, primary Bayesian network meta-analysis outputs, prespecified sensitivity outputs, netmeta assumption diagnostics, targeted sensitivity analyses, leave-one-study-out diagnostics, GRADE-NMA comparison-level adjudication, endpoint-level claim ledger, PRISMA audit files, report-level abstract/registry audit, SHA256 manifests, source-of-truth lock files, internal validation, static output audit, and the confirmed external clean R/JAGS rerun PASS addendum. Canonical counts: 42 included studies, 27 SAR studies, 15 PAR studies, approximately 21,635 randomized participants, 115 efficacy arm rows, 196 safety arm rows, 11 feasible endpoint networks, one non-feasible endpoint network (PAR_TOSS), 162 GRADE-NMA key comparisons, and 67 leave-one-study-out netmeta checks. The final external computational audit status is PASS_EXTERNAL_CLEAN_RJAGS_RERUN_CONFIRMED. The canonical archive is antiH1_NMA_source_of_truth_v3_0_FINAL_DEPOSIT_READY.zip. Its SHA256 is 759386b5f3c56f3b7235d60537c797e5981a6fee71f79210c82567bd7f32eae6. Full-text publisher PDFs are not redistributed. Users should obtain full-text articles through lawful institutional or publisher access.