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Crystal structure of PT2385 bound to HIF2a-B*:ARNT-B* complex

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Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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Crystal structure of PT2385 bound to HIF2a-B*:ARNT-B* complex Descriptor: 3-{[(1S)-2,2-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl]oxy}-5-fluorobenzonitrile, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1 Authors: Du, X. Deposit date: 2016-09-12 Release date: 2016-09-21 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.85 Å) Cite: A Small-Molecule Antagonist of HIF2 alpha Is Efficacious in Preclinical Models of Renal Cell Carcinoma. Cancer Res., 76, 2016

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2016-09-12
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