Gene expression profiling was performed of Pax5 wild type bone marrow subsets from common lymphoid progenitors through to Hardy stage F cells. These cells were obtained by flow sorting of bone marrow.

NIAID Data Ecosystem40

Investigation of Gata2 L359V mutation in hematopoiesis and leukemogenesis

造血分化异常

白血病基因组

GATA2, an essential transcription factor in fetal and adult hematopoiesis, is frequently found to be mutated in hematopoietic malignancies. However, the function of mutated GATA2 in hematopoiesis and

NIAID Data Ecosystem30

Affymetrix SNP6.0 array data for PAX5 amplified acute lymphoblastic leukemia

白血病基因组

肿瘤基因扩增分析

Intragenic PAX5 amplification in <1%of B-cell precursor acute lymphoblastic leukaemia. Affymetrix SNP 6.0 array analysis was undertaken in patients who showed amplication of PAX5 by MLPA testing usi

NIAID Data Ecosystem40

Primers and probes for 3-plex RT-qPCR of PML-RARa and ABL.

白血病基因组

RT-PCR引物设计

aProbe (r) = Reverse TaqMan MGB probe; PML primer 1 for bcr1, bcr2 and bcr3; PML primer 5 for bcr1 and bcr2; PML primer 6 for bcr3Primers and probes for 3-plex RT-qPCR of PML-RARa and ABL.

Figshare2015-12-03 更新30

Array genotyping of 173 children with acute lymphocytic leukemia (ALL)

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