Different HIV/SIV vaccine vectors expressing the same viral antigens can elicit disparate T-cell responses. Within this spectrum, replicating variable vaccines like SIVmac239?nef appear to generate pa
Type I interferon upregulates proteins that inhibit HIV replication within infected cells. Here, we characterize IFN-induced gene expression in HIV target cells, primary CD4+ T cells, isolated from se
Data from Laboratory Results Form: HIV Viral Load Assessment [CRF 6] Study Description An exploratory laboratory-based evaluation of cellular immune response to immunization with hepatitis B surface a
HIV-1 infection of monocyte-derived macrophages does not elicit a detectable type I IFN response in vitro, however, previously published data has shown that blocking STAT1 and STAT3 inhibits HIV-1 rep
