Multimodality annotated HCC cases with and without advanced imaging segmentation

<p>Hepatocellular carcinoma (HCC) is the most common primary liver cancer with incidences doubled over the past two decades due to increasing risk factors. Despite surveillance, the majority of HCC cases are diagnosed at advanced stages that can be treated only using (Transarterial chemoembolization) TACE, or systemic therapy. TACE failure can occur to 60% of patients receiving the procedure, with subsequent financial and emotional burden. Radiomics have emerged as a new tool capable of predicting tumor response to TACE from pre-procedural CT study.</p><p>This retrospectively acquired data collection includes pre- and post-procedure CT imaging studies of 105 confirmed HCC patients who underwent TACE between 2002 and 2012 with an available treatment outcome, in the form of time-to-progression and overall survival. Baseline imaging includes multiphasic contrast-enhanced CT with no image artifacts (e.g. surgical clip) and was obtained 1-12 weeks (average 3 weeks) prior to the first TACE session. Semiautomatic segmentation of liver, tumor, and blood vessels created using <a href="https://assets.thermofisher.com/TFS-Assets/MSD/Product-Guides/users-guide-amira-software-2019.pdf">AMIRA </a>was manually clinically curated. These segmentations of each pre-procedural CT study were done for the purpose of algorithm training for prediction and automatic liver tumor segmentation, and are provided here (NIfTI converted to DICOM-SEG format).</p>肝细胞癌（HCC）是最常见的原发性肝癌，其发病率在过去二十年里翻倍，这主要归因于风险因素的日益增加。尽管存在监测，但大多数HCC病例在晚期被诊断，此时只能通过（经动脉化疗栓塞术）TACE或全身治疗来治疗。接受该手术的患者中，TACE失败率可高达60%，随之而来的是经济和情感上的负担。放射组学作为一种新兴工具，能够从术前CT研究中预测肿瘤对TACE的反应。本数据集为回顾性收集的数据，包括2002年至2012年间接受TACE治疗的105例确诊HCC患者的术前和术后CT影像学检查。基线影像包括无图像伪迹（例如手术夹）的多期对比增强CT，并在首次TACE会话前1-12周（平均3周）获得。使用AMIRA（见https://assets.thermofisher.com/TFS-Assets/MSD/Product-Guides/users-guide-amira-software-2019.pdf）软件进行的肝脏、肿瘤和血管的半自动分割已进行临床人工校准。这些术前CT研究的分割是为了算法训练以预测和自动进行肝脏肿瘤分割，并已提供（NIfTI转换为DICOM-SEG格式）。

搜集汇总

背景与挑战

背景概述

该数据集是一个回顾性收集的多模态肝细胞癌（HCC）病例数据集，包含105名患者在2002年至2012年间接受TACE治疗前后的CT影像研究，并提供了治疗结果。数据集特点包括使用多期对比增强CT进行基线影像采集，无图像伪影，并提供了经过手动临床审核的肝脏、肿瘤和血管半自动分割数据（以DICOM-SEG格式），旨在用于算法训练以预测TACE反应和实现自动肿瘤分割。这有助于研究HCC的影像学特征和TACE治疗效果的预测模型开发。