Next-Generation Sequencing Facilitates Quantitative Analysis of WT and Mpp8/Tasor double knockout Embryonic Stem Cells Transcriptomes

Purpose: The goals of this study are to compare Mpp8/Tasor-dko with wildtype embryonic stem cells transcriptome profiling (RNA-seq) to evaluate the target genes regulated by HUSH complex. Overall design: mRNA profiles of WT and MPP8/Tasor-dko embryonic stem cells were generated by deep sequencing, in triplicate, using Illumina Novaseq6000.