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Figure S1 - Inhibition of DNA Glycosylases via Small Molecule Purine Analogs

NIAID Data Ecosystem2026-03-08 收录

数据链接：

https://figshare.com/articles/dataset/_Inhibition_of_DNA_Glycosylases_via_Small_Molecule_Purine_Analogs_/872532 数据链接链接失效反馈

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资源简介：

Compounds of interest from the HTS of a purine analog library. (PDF)

应用场景：

创建时间：

2013-12-09

蛋白质晶体学

糖基化抑制

Crystal structure of human O-GlcNAc transferase bound to a peptide from HCF-1 pro-repeat 2 (11-26) and inhibitor 3a Descriptor: 5-{2-[(1R)-2-{(carboxymethyl)[(thiophen-2-yl)methyl]amino}-2-oxo-1-{[(2-

Protein Data Bank Japan2023-10-11 更新60

Golgi alpha-Mannosidase II in complex with Mannostatin analog (1R,2R,3S,4R,5R)-5-aminocyclopentane-1,2,3,4-tetraol

酶结构解析

糖基化抑制

Golgi alpha-Mannosidase II in complex with Mannostatin analog (1R,2R,3S,4R,5R)-5-aminocyclopentane-1,2,3,4-tetraol Descriptor: (1R,2R,3S,4R,5R)-5-aminocyclopentane-1,2,3,4-tetrol, (4R)-2-METHYLPENTANE

Protein Data Bank Japan2024-10-30 更新30

XcOGT in complex with UDP-S-GlcNAc

O-GlcNAc转移酶

糖基化抑制

XcOGT in complex with UDP-S-GlcNAc Descriptor: URIDINE-DIPHOSPHATE-1-DEOXY-1-THIO-N-ACETYLGLUCOSAMINE, XCOGT Authors: Dorfmueller, H.C, Borodkin, V.S, Blair, D.E, Pathak, S, Navratilova, I, van Aalten

Protein Data Bank Japan2023-12-20 更新30

2-DG protects mouse from DSS-induced inflammatory bowel disease

结肠炎机制

糖基化抑制

Anti-proinflammatory cytokine therapies against interleukin (IL)-6 and tumor necrosis factor (TNF)-a are major advances in treating inflammatory diseases. We found that 2-deoxy-D-glucose (2-DG), a sim

NIAID Data Ecosystem40

The crystal structure of SAUGI/human UDG complex

UDG复合物晶体结构

糖基化抑制

The crystal structure of SAUGI/human UDG complex Descriptor: MAGNESIUM ION, Uncharacterized protein, Uracil-DNA glycosylase Authors: Wang, H.C, Ko, T.P, Huang, M.F, Wang, A.H.J. Deposit date: 2015-09-

Protein Data Bank Japan2023-11-08 更新30

Figure S1 - Inhibition of DNA Glycosylases via Small Molecule Purine Analogs

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