Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma

ChEBI2016-03-25 更新2026-07-12 收录

癌细胞代谢

肝细胞癌病因

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-79535 数据链接链接失效反馈

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资源简介：

Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma

创建时间：

2016-03-25

Model simulation results for 5 experiments on suspensions of Ehrlich ascites tumor cells in vitro.

癌细胞代谢

模型模拟

Experiment 1: low glucose concentration added (92 µM); Experiment 2: higher glucose concentration added (776 μM); Experiment 3: one hour aerobic incubation with high concentration of glucose (11.1 mM)

DataCite Commons2020-09-20 更新60

Midnolin Regulates Liver Cancer Cell Growth In Vitro and In Vivo. Midnolin Regulates Liver Cancer Cell Growth In Vitro and In Vivo

肝细胞癌病因

基因功能研究

Hepatocellular carcinoma (HCC) ranks worldwide as one of the most lethal cancers. In spite of the vast existing knowledge about HCC, the pathogenesis of HCC is not completely understood. Discovery of

NIAID Data Ecosystem50

Crystal structure of human PHGDH complexed with Compound 15

PHGDH抑制剂结构

癌细胞代谢

Crystal structure of human PHGDH complexed with Compound 15 Descriptor: (2S)-(4-{3-[(4,5-dichloro-1-methyl-1H-indole-2-carbonyl)amino]oxetan-3-yl}phenyl)(pyridin-3-yl)acetic acid, D-3-phosphoglycerate

Protein Data Bank Japan2024-11-06 更新40

β-Caryophyllene Enhances the Transcriptional Upregulation of SREBP-dependent Lipid Biosynthesis in Breast Cancer Cells

癌细胞代谢

SREBP信号通路调控

β-caryophyllene (BCP) exhibits anti-proliferative properties in cancer cells. Here, we examine the hypothesis that BCP induces membrane remodeling. Our data show that high concentrations of BCP incr

NIAID Data Ecosystem60

Metabolites_310K_pH4.zip

癌细胞代谢

代谢组学分析

Dataset for "Rapid Probing of Glucose Influx into Cancer Cell Metabolism: Using Adjuvant and a pH-Dependent Collection of Central Metabolites to Improve In-Cell D-DNP NMR". NMR spectroscopy spectra fo

DataCite Commons2023-08-28 更新40

Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma

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