RNA-seq analysis on organoids derived from metastatic tumor patients

To evaluate the efficiency of apatinib on vascularized patient-derived tumor organoids (PDTOs)-on-a-chip derived from patients with metastatic tumors, we conducted RNA-seq analysis on organoids derived from patients whom had metastatic tumors. Specifically, we extracted RNA for sequencing from tumor cells of organoids either cultured alone or co-cultured with MVs with or without apatinib treatment Overall design: RNA-Seq from tumor cells of organoids either cultured alone or co-cultured with MVs with or without apatinib treatment