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Somatic Hypermutation in transgenic 3BNC117 coding genes of engineered mouse B cells

NIAID Data Ecosystem2026-03-12 收录

体细胞高频突变

抗体工程

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA706552 数据链接链接失效反馈

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Comparative sequencing of Liver and Spleen tissue.

应用场景：

创建时间：

2021-03-04

结构生物学

抗体工程

Llama nanobody n02 raised against EAEC T6SS TssM Descriptor: Llama nanobody n02 VH domain Authors: Nguyen, V.S, Desmyter, A, Le, T.T.H, Durand, E, Kellenberger, C, Douzi, B, Spinelli, S, Cascales, E,

Protein Data Bank Japan2024-10-16 更新60

Crystal structure of homo-specific diabody

蛋白质晶体

抗体工程

Crystal structure of homo-specific diabody Descriptor: homo-specific diabody protein Authors: Kim, J.H, Song, D.H, Youn, S.J, Kim, J.W, Cho, G, Lee, H, Lee, J.O. Deposit date: 2016-08-12 Release date:

Protein Data Bank Japan2024-10-09 更新40

Table S1 - High Affinity Humanized Antibodies without Making Hybridomas; Immunization Paired with Mammalian Cell Display and In Vitro Somatic Hypermutation

抗体工程

药物研发

List of primers used for amplification of CDRH3 diversity from immunized mice. Uppercase nucleotides represent Eag I (CGGCCG) and Nhe I (GCTAGC) Type II restriction sites for cloning purposes. Lowerca

Figshare2015-12-02 更新30

ADAPT consensus Z-scores used in VHH-72 mutation selection.

抗体工程

突变体筛选

ADAPT consensus Z-scores used in VHH-72 mutation selection.

NIAID Data Ecosystem50

Data and model weights for a series of antibody language models

抗体工程

蛋白质语言模型

This repo contains the sequence dataset for finetuning and model weights including pre-trained meta model and a series of finetuned antibody language models. The antibody language models were used in

NIAID Data Ecosystem30

Somatic Hypermutation in transgenic 3BNC117 coding genes of engineered mouse B cells

资源简介：

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