BindingDB

BindingDB收录蛋白质与小分子配体之间的实验测定结合亲和力、靶点、化合物结构、文献来源和药物发现相关数据；由BindingDB团队提供，用于药理学、化学生物学和先导化合物筛选研究。

BindingDB curates experimentally determined binding affinities, target proteins, compound structures, literature sources, and drug discovery-related data for interactions between proteins and small-molecule ligands. The dataset is provided by the BindingDB team and is intended for research in pharmacology, chemical biology, and lead compound screening.

搜集汇总

背景与挑战

背景概述

BindingDB是首个公开的分子识别数据库，专注于收录蛋白质与小分子配体之间的实验测定结合亲和力数据，包含数百万条化合物与靶点信息。该数据库作为FAIR共享资源，支持药物发现、药理学及相关领域的研究与应用。