Immune cell expression profiles of hub genes in ulcerative colitis.

Figshare2026-01-02 更新2026-04-28 收录

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Immune cell expression profiles of hub genes in ulcerative colitis.

创建时间：

2026-01-02

OTUD3 prevents ulcerative colitis by modulating microbiota-mediated STING activation

猪肠道免疫学

结肠炎机制

Human intestinal Thy1+ mesenchymal cells are considered as heterogeneous population. We performed single cell RNA sequencing (scRNA-seq) to characterize fibroblast populations in the colonic mucosa.Li

NIAID Data Ecosystem30

TNFSF13 insuffiency causes epithelial and immune disruption in the human colon I

结肠炎机制

结肠上皮-免疫互作

Objective: Cytokines produced by epithelial and immune cells can act upon one another to promote mucosal healing- a process that goes awry with chronic inflammation as in inflammatory bowel disease. T

NIAID Data Ecosystem00

Type III interferons induce pyroptosis in gut epithelial cells and impair tissue repair upon intestinal injury.

肠道上皮细胞焦亡

结肠炎机制

Tissue damage and repair are hallmarks of the inflammatory process. Despite a wealth of information on the mechanisms that govern tissue damage, mechanistic insight on how inflammatory mediators affec

NIAID Data Ecosystem00

Gene expression profiles of human memory B cells stimulated with BCR/CD40L/IFN-γ/IL21. Gene expression profiles of human memory B cells stimulated with BCR/CD40L/IFN-γ/IL21

细胞基因表达

IL-23信号通路

Analysis of the effect of BCR/CD40/IFN-γ/IL21 on human B cells at gene expression level. Overall design: Total RNA samples were obtained from human memory B cells subjected to 24 hours of in vitro cul

NIAID Data Ecosystem30

CCDC88B interacts with RASAL3 and ARHGEF2 to regulate dendritic cell function in neuroinflammation and colitis. CCDC88B interacts with RASAL3 and ARHGEF2 to regulate dendritic cell function in neuroinflammation and colitis

树突状细胞迁移

结肠炎机制

CCDC88B is a risk factor for several chronic inflammatory diseases in humans and its inactivation causes a migratory defect in DCs in mice. CCDC88B belongs to a family of cytoskeleton-associate scaffo

NIAID Data Ecosystem00

Immune cell expression profiles of hub genes in ulcerative colitis.

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