The goal of the study was to obtain plasmid containing the SAT1 Flipper knockout cassette along with upstream and downstream gene fragments (STR2) and to introduce a cleavage site for restriction enzy
In this study, the glutamine synthetase gene and fut8 gene were simultaneously knocked out in CHO cells with CRISPR/Cas 9 technology and homologous replacement.
We generated a mouse model (ARLmon/Y) with disrupted dimerization of the ligand-binding domain 25 (LBD) of the androgen receptor (AR). These mice exhibit an external female phenotype with undescended
The two estrogen receptors, ERα and ERβ function as ligand-inducible transcription factors. Most in vitro studies have reported that ERα drives breast cancer growth whereas ERβ, if expressed, suppress
