Catalytic Enantioselective Synthesis of Aryl–Methyl Organophosphorus Compounds
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A catalytic enantioselective protocol for the synthesis of aryl–methyl organophosphorus compounds is reported. Utilizing a chiral phosphoric acid as a catalyst, a wide range of indole derivatives reacted with phosphorylated quinomethanes in high yield with excellent enantioselectivity. This is the first report on the application of phosphorylated quinomethanes in asymmetric synthesis.
创建时间：
2021-01-06
