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Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation

ChEBI2015-01-26 更新2026-07-21 收录

DNA复制酶学

基因组稳定性

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-62181 数据链接链接失效反馈

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Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation

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创建时间：

2015-01-26

表观遗传调控

基因组稳定性

Histone H3.3 is a highly conserved histone H3 replacement variant in metazoans, and has been implicated in many important biological processes including cell differentiation and reprogramming. Germlin

NIAID Data Ecosystem80

BLM prevents instability of structure-forming DNA sequences at common fragile sites

基因组稳定性

DNA修复

Genome instability often arises at common fragile sites (CFSs) leading to cancer-associated chromosomal rearrangements. However, the underlying mechanisms of how CFS protection is achieved is not well

Figshare2018-12-11 更新50

Whole-genome sequencing analysis of CRISPR-tolerant mutants. Escherichia coli

CRISPR系统

基因组稳定性

To investigate whether ISs transpositions into cas genes could potentially lead to concurrent transpositions into other genomic loci or induce genomic rearrangements and instability, we performed whol

NIAID Data Ecosystem40

Expansions and Contractions in a Tandem Repeat Induced by Double-Strand Break Repair

基因组稳定性

DNA损伤修复

Repair of a double-strand break (DSB) in yeast can induce very frequent expansions and contractions in a tandem array of 375-bp repeats. These results strongly suggest that DSB repair can be a major s

PubMed Central60

Effect of plastid transcription on genome integrity in Arabidopsis

基因组稳定性

R-loop介导的基因组不稳定性

Transcription can be an important natural source of genome instability. For instance, it may generate RNA:DNA hybrids as the nascent transcript hybridizes with the complementary DNA template. These hy

NIAID Data Ecosystem40

Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation

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