The human blood-nerve barrier transcriptome. The human blood-nerve barrier transcriptome

We report the application of whole exome sequencing to comprehensively deduce the normally conserved transcript profile of endoneurial endothelial cells that form the adult human blood-nerve barrier by combining in vitro and in situ analyses Overall design: Examination of early and late passage primary human endoneurial endothelial cells combined with laser capture microdissected endoneurial microvessels from 4 histologically normal cryopreserved adult sural nerve biopsies