Mutations found in patients failing regiments containing LPV/r or NNRTIs.

Mutations found in patients failing regiments containing LPV/r or NNRTIs. The Table classifies patients failing on LPV/r or NNRTI containing regimens according to the number of mutations conferring resistance to the different drug classes. “+” indicates presence of mutations, but for some patients the actual mutations are listed. “–” indicates “no mutations” or also “no previous PI-containing regimens”. EFV – efavirenz; IDV – indinavir; LPV/r – lopinovir/ritonavir; NFV – nelfinavir; NNRTIs – Non-nucleosides reverse transcriptase inhibitors; NRTIs – Nucleosides reverse transcriptase inhibitors; NVP – nevirapine; SQV – saquinavir; PIs – protease inhibitors.