Functional annotation of CPGs subject to positive selection.

Predicted cellular location based on GPI signal peptide and transmembrane domain prediction for each member of each cluster (see methods) Su; surface, Se; secreted, In; Intracellular. Pfam domains were detected using HMMER [47] to search the Pfam database [54]. Gene Ontology terms were linked to predicted Pfam domains using Pfam2GO (http://www.geneontology.org/). For details of gene annotation and prediction of location see methods.