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Combined oncolytic adenovirus DNX-2401 and anti-PD-checkpoint inhibitor pembrolizumab for recurrent glioblastoma

NIAID Data Ecosystem2026-05-01 收录

胶质母细胞瘤联合免疫治疗

溶瘤病毒疗法

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE226976 数据链接链接失效反馈

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资源简介：

Gene expression data for samples included in this trial of DNX2401 and pembrolizumab for recurrent glioma Observational cohort CAPTIVE investigators

应用场景：

创建时间：

2023-05-19

病毒致病机制

溶瘤病毒疗法

Chikungunya virus (CHIKV), an arthritogenic old-world alphavirus, has been implicated in the central nervous system (CNS) infection in infants and elderly patients. Astrocytes are the major immune cel

NIAID Data Ecosystem100

Supplementary Material for: Case Report Oncolytic Virotherapy for Relapsed IDH-mutant, grade 3 Astrocytoma – a New Promising Approach: Case Report

溶瘤病毒疗法

神经内分泌肿瘤临床研究

Introduction: IDH-mutant astrocytomas are high-grade gliomas with a poor prognosis. Transformation to glioblastoma multiforme (GBM) is common, which further shortens OS and frequently renders the tumo

DataCite Commons2025-03-06 更新70

Single-cell RNA sequencing reveals a strong connection between Gadd45g upregulation and oncolytic HSV infection in tumor tissue

溶瘤病毒疗法

单细胞RNA测序

The oncolytic effect of virotherapy derives from the intrinsic capability of the applied virus in selectively infecting and killing tumor cells. Although oncolytic viruses of various constructions hav

NIAID Data Ecosystem20

Additional file 4 of Safety studies and viral shedding of intramuscular administration of oncolytic vaccinia virus TG6002 in healthy beagle dogs

溶瘤病毒疗法

临床前安全性评价

Additional file 4. Detection of virus shedding by plaque assay after three intramuscular injections of TG6002. Infectious VACV was not detected in blood, urine and saliva samples by plaque assay from

NIAID Data Ecosystem70

Transcriptome sequencing of SKOV3 cells and COC1/DDP cells

卵巢癌耐药性

溶瘤病毒疗法

SKOV3 are reovirus-sensitive ovarian cancer cells and COC1/DDP are reovirus-resistant ovarian cancer cells of ascites origin.The analysis of the two strains of cells subjected to transcriptome sequenc

NIAID Data Ecosystem20

Combined oncolytic adenovirus DNX-2401 and anti-PD-checkpoint inhibitor pembrolizumab for recurrent glioblastoma

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