Induction of alpha cell-restricted Gc in dedifferentiating beta cells contributes to stress-induced beta-cell dysfunction [RNA-seq]
收藏NIAID Data Ecosystem2026-04-25 收录
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资源简介：
To identify effector genes of pancreatic beta cell dedifferentiation and dysfunction, we performed RNA expression in beta cells sorted from mice with multiparity-induced diabetes. Overall design: We performed RNAseq in FAC-sorted beta cells from female mice. There are a total of 6 conditions: 3-month-old nulliparous WT and RIP-Cre/FoxO1 floxed (IKO) mice, 12-month-old nulliparous WT and IKO mice, and 12-month-old multiparous WT (labeled as NGT) and IKO (labeled as DM) mice.
创建时间：
2019-11-02
