Intra-islet crosstalk between islet cells is critical in orchestrating the bodyâs response to changes in blood glucose levels, but is incompletely understood. In this study, we used transgenic mouse

NIAID Data Ecosystem60

Next Generation Sequencing Facilitating Quantitative Analysis of Wild Type (Kcnj11fl/fl, WT) and β-cell Specific Kcnj11 -/- (βKcnj11 -/-, bKO) Mouse Islets' Transcriptomes. Next Generation Sequencing Facilitating Quantitative Analysis of Wild Type (Kcnj11fl/fl, WT) and β-cell Specific Kcnj11 -/- (βKcnj11 -/-, bKO) Mouse Islets' Transcriptomes

胰腺转录组学

基因敲除小鼠转录组

β-cell Specific Kcnj11 -/- mice and their islets exhibited a hirtherto unkown switch in the major signaling pathway of G-protein coulpled receptors from Gs to Gq, and overall enhanced Gq signaling. Th

NIAID Data Ecosystem50

RNAseq analysis of 8week old islets from murine Abca12 KO pancreas. RNAseq analysis of 8week old islets from murine Abca12 KO pancreas

胰腺转录组学

基因敲除功能研究

The goal of this study was to identify changes in the transcriptome that occur following Abca12 gene deletion relative to Control islets Overall design: Islets were isolated from 8 week old mice from

NIAID Data Ecosystem60

CAF study - Monoamine + redox data.xlsx

神经递质分析

高脂饮食代谢

Concentrations of monoamine neurotransmitters and their metabolites and of redox markers in the prefrontal cortex and hippocampus of male Sprague-Dawley rats fed a Cafeteria Diets for 5 months on a re

NIAID Data Ecosystem50

Transcription profiling of mouse AKR/J and C57Bl/6J strain pancreatic islets from high fat fed

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