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Bmal1 controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis

ChEBI2012-08-01 更新2026-07-21 收录

皮肤生物钟调控

UV诱导DNA损伤

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-38625 数据链接链接失效反馈

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资源简介：

Bmal1 controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis

应用场景：

创建时间：

2012-08-01

UV诱导DNA损伤

乳腺上皮细胞基因表达

For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf https://www.e

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Elevated pyrimidine dimer formation at distinct genomic bases underlies promoter mutation hotspots in UV-exposed cancers

UV诱导DNA损伤

皮肤癌机制

Sequencing of whole cancer genomes has revealed an abundance of recurrent mutations in gene-regulatory promoter regions, in particular in melanoma where strong mutation hotspots are observed adjacent

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Nucleosome positions establish an extended mutation signature in melanoma

UV诱导DNA损伤

核小体突变特征

Ultraviolet (UV) light-induced mutations are unevenly distributed across skin cancer genomes, but the molecular mechanisms responsible for this heterogeneity are not fully understood. Here, we assesse

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Sequence Dependent UV Damage of ACACNNNNNNNNACAC ssDNA

UV诱导DNA损伤

高通量测序

ssDNA strands of the form ACAC NNNNNNNN ACAC are exposed to various doses of 266nm radiation up to dosages of 200 absorbed photons per base. The resulting samples are prepared for sequencing using com

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Whole Genome Expression Profiling shows that BRG1 Transcriptionally Regulates UV Inducible Genes and other Novel Targets in Human Cells

BRG1转录调控

UV诱导DNA损伤

BRG1, an ATPase catalytic subunit of the SWI/SNF chromatin remodeling complex, has been identified as a tumor suppressor protein, as it has been shown to play a role in Nucleotide Excision Repair (NER

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Bmal1 controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis

资源简介：

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