The aim of this study was to analyze the gene expression profile for three main cell lines (supporting, interstitial/stromal, and germ cells) isolated from developing gonads at the critical period of
In mouse primary sex determination, SRY directly upregulates the expression of SOX9, the master regulatory transcription factor in Sertoli cell differentiation around at 11.5 d.p.c. Without SRY action
Animals were raised and scored as described in Methods. Genotypes are as in Table 1. Z test for two population proportions was used to assess signifcance (p<0.05) of differences between different valu