Couple transcriptome and genomic data obtained from the PDXs to identify pathways linking oncogenic alterations
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Purpose: Study the changes in cell transcriptome in breast cancer with respect to normal breast tissue in association with somatic mutations Methods: RNA was extracted from frozen normal breast tissues and PDXs cells Results: We found over-expression of oncogenic pathways associated with oncogenic mutations in PDXs Analysis of differential gene expression in metastatic breast cancer PDXs
创建时间：
2019-07-30
