Fc Heterodimer Design 6.1 F405W/Y407A + T366M
收藏资源简介：
Fc Heterodimer Design 6.1 F405W/Y407A + T366M Descriptor: Fc-III peptide, Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose Authors: Atwell, S, Leaver-Fay, A, Froning, K.J, Aldaz, H, Pustilnik, A, Lu, F, Huang, F, Yuan, R, Dhanani, S.H, Chamberlain, A.K, Fitchett, J.R, Gutierrez, B, Hendle, J, Demarest, S.J, Kuhlman, B. Deposit date: 2015-09-01 Release date: 2016-03-30 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Computationally Designed Bispecific Antibodies using Negative State Repertoires. Structure, 24, 2016
Fc异二聚体设计6.1：F405W/Y407A + T366M 描述项：Fc-III肽（Fc-III peptide）、免疫球蛋白γ-1链C区（Ig gamma-1 chain C region）、β-D-吡喃半乳糖-(1→4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1→2)-α-D-吡喃甘露糖-(1→6)-[α-D-吡喃甘露糖-(1→3)]β-D-吡喃甘露糖-(1→4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1→4)-[α-L-吡喃岩藻糖-(1→6)]2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖 作者：Atwell, S.、Leaver-Fay, A.、Froning, K.J.、Aldaz, H.、Pustilnik, A.、Lu, F.、Huang, F.、Yuan, R.、Dhanani, S.H.、Chamberlain, A.K.、Fitchett, J.R.、Gutierrez, B.、Hendle, J.、Demarest, S.J.、Kuhlman, B. 存入日期：2015-09-01 发布日期：2016-03-30 最后修改时间：2024-11-13 实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率2 Å） 引用文献：《使用负态库计算设计双特异性抗体》（Computationally Designed Bispecific Antibodies using Negative State Repertoires），《Structure》，第24卷，2016年
