THE STRUCTURE OF PHOSPHOTYROSINE PHOSPHATASE 1B IN COMPLEX WITH COMPOUND 2

THE STRUCTURE OF PHOSPHOTYROSINE PHOSPHATASE 1B IN COMPLEX WITH COMPOUND 2 Descriptor: Protein-tyrosine phosphatase, non-receptor type 1, [4-(2-(1H-1,2,3-BENZOTRIAZOL-1-YL)-3-{4-[DIFLUORO(PHOSPHONO)METHYL]PHENYL}-2-PHENYLPROPYL)PHENYL](DIFLUORO)METHYLPHOSPHONIC ACID Authors: Scapin, G, Patel, S.B, Becker, J.W, Wang, Q, Desponts, C, Waddleton, D, Skorey, K, Cromlish, W, Bayly, C, Therien, M, Gauthier, J.Y, Li, C.S, Lau, C.K, Ramachandran, C, Kennedy, B.P, Asante-Appiah, E. Deposit date: 2003-08-13 Release date: 2003-09-30 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.2 Å) Cite: The Structural Basis for the Selectivity of Benzotriazole Inhibitors of Ptp1B Biochemistry, 42, 2003与化合物2结合的蛋白酪氨酸磷酸酶1B结构 描述：非受体型蛋白酪氨酸磷酸酶1型（Protein-tyrosine phosphatase, non-receptor type 1）与配体[4-(2-(1H-1,2,3-苯并三唑-1-基)-3-{4-[二氟(膦酰基)甲基]苯基}-2-苯基丙基)苯基]二氟甲基膦酸 作者：Scapin, G、Patel, S.B、Becker, J.W、Wang, Q、Desponts, C、Waddleton, D、Skorey, K、Cromlish, W、Bayly, C、Therien, M、Gauthier, J.Y、Li, C.S、Lau, C.K、Ramachandran, C、Kennedy, B.P、Asante-Appiah, E. 存储日期：2003-08-13 发布日期：2003-09-30 最后修改日期：2023-08-16 实验方法：X射线衍射（分辨率2.2 Å） 引用文献：《PTP1B苯并三氮唑类抑制剂选择性的结构基础》，《生物化学（Biochemistry）》，2003年第42卷