We studied how crosstalk with disseminated dormant breast cancer cells affects transcriptome of AT1-like cells and the requirement of EphB6 expression in the cancer cells for this genetic program Over
Cancer-associated fibroblasts (CAFs) are key components in tumor microenvironment (TME). The secreted products of CAFs play important roles in regulating tumor cells and further impacting clinical pro
Pancreatic ductal adenocarcinoma (PDAC) features substantial matrix stiffening and reprogrammed glucose metabolism, particularly the Warburg effect. However, the complex interplay between these traits
PurposeTo systematically investigate the characterization of tumor microenvironment (TME) in clear cell renal cell carcinoma (ccRCC), we performed a comprehensive analysis incorporating genomic altera
We performed spatial transcriptomics on primary cutaneous melanoma samples to characterise the tumour microenvironment Overall design: Two primary cutaneous melanoma FFPE samples were analysed using s
