Leucine zipper-based sorting system enables generation of multi-functional CAR T cells

NIAID Data Ecosystem2026-05-01 收录

CART细胞工程

基因整合位点分析

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1052637 数据链接链接失效反馈

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资源简介：

Comparing integration site distribution in dual versus single transduced samples.

创建时间：

2023-12-14

mappings

基因整合位点分析

胚胎干细胞研究

piggyBac vector integration sites in mouse embryonic stem cells. Mapped to mouse genome m38. Insertion site is in the form: [chromosome][strand:+/-][position]. The number is the number of reads mappin

Figshare2016-07-01 更新70

Epigenetically programmed ‘stem-like’ tissue resident memory CAR T-cells exhibit robust activity against solid and liquid tumors [scRNA]. Epigenetically programmed ‘stem-like’ tissue resident memory CAR T-cells exhibit robust activity against solid and liquid tumors [scRNA]

CART细胞工程

肿瘤免疫治疗

Chimeric antigen receptor (CAR) T-cells have shown remarkable success in the therapy of hematological malignancies, but they have not yet proven nearly as effective in treating non-hematopoietic cance

NIAID Data Ecosystem50

RAISING: a high-performance method for identifying random transgene integration sites. Mammalia

基因整合位点分析

基因治疗评估

Virus and viral vector integration into a host genome have risks associated with various diseases, including cancers. Currently, RAIS (Rapid Amp lification of Integration Site) and the other next gene

NIAID Data Ecosystem40

TLA sequencing for CamiCre mice

转基因小鼠模型

基因整合位点分析

The CamiCre, one of the widely used CamK2a-Cre mouse lines, has shown abnormalities on the molecular level when compared to wild-type controls. We performed the TLA analysis in order to: 1- Study the

NIAID Data Ecosystem60

Identification of gene insertion sites in transgenic mice overexpressing mouse carbonyl reductase 1

基因整合位点分析

CBR1功能机制研究

Carbonyl reductase 1 (CBR1) participates in various cellular processes, such as signal transduction, apoptosis, carcinogenesis, and drug resistance. Previous studies showed that ovarian cancer progres

NIAID Data Ecosystem50

Leucine zipper-based sorting system enables generation of multi-functional CAR T cells

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