Cell-surface binding and solution state properties of HER2 agonists and antagonists.
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†All molecules in this table are derived from trastuzumab. LC = light chain; HC = heavy chain. Numbers indicate the cysteine substitution position. ‡Activity was determined by cell proliferation assays using BT474 cells. Rhyd = hydrodynamic radius determined by size exclusion chromatography coupled-light scattering. Standard deviation is represented by +/− values in the table.
创建时间：
2012-12-20
