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Comparison of non-coding RNAs in exosomes and functional efficacy of human embryonic stem cell- versus induced pluripotent stem cell-derived cardiomyocytes
To understand the exosomal secretome of ESC-CMs and iPSC-CMs, samples were analyzed using the Human LncRNA Array v4.0 (8 x 60K, Arraystar) Two independent lines for both ESC-CMs and iPSC-CMs were used
NIAID Data Ecosystem70
Large particle fluorescence-activated cell sorting enables high quality single cell RNA-sequencing and functional analysis of adult cardiomyocytes. Large particle fluorescence-activated cell sorting enables high quality single cell RNA-sequencing and functional analysis of adult cardiomyocytes
The use of single cell RNA sequencing (scRNA-seq) remains limited in cardiac pathology owing to technical difficulties associated with the isolation of single adult cardiomyocytes (CMs). Here, we inve
NIAID Data Ecosystem40
Effects of DECR1 deletion on cardiomyocytes
To elucidate the non-ischemic roles of Decr1 in cardiomyocytes, we studied the phenotypic effects of its knockdown in the absence of ischemic or hypoxic stress. Overall design: The study comprised two
NIAID Data Ecosystem20
RNAseq analysis for cardiomyocyte-specific Fam64a TG mice
We have recently identified Fam64a as a fetal-specific gene, the primary function of which is promoting cardiomyocyte cell cycle. To gain deeper insight into the molecular function of Fam64a, we analy
NIAID Data Ecosystem50
Moderate Continuous Aerobic Exercise Training Improves Cardiomyocyte Contractility in Β1 Adrenergic Receptor Knockout Mice
Abstract Background: The lack of cardiac β1-adrenergic receptors (β1-AR) negatively affects the regulation of both cardiac inotropy and lusitropy, leading, in the long term, to heart failure (HF). Mod
Figshare2018-02-01 更新30



