Upstream network analysis of HNF4A.

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Upstream network analysis of HNF4A.

创建时间：

2021-10-01

Upstream network analysis of HNF4A.

Figshare2021-10-01 更新20

Characterization of genome-wide DNA binding rhythms of HNF4A. Characterization of genome-wide DNA binding rhythms of HNF4A

HNF4A mRNA cycles over the coure of 24 h. To understand whether the chromatin binding of the transcription factor is also rhythmic, we performed ChIP-seq for HNF4A using mouse liver samples of ZT4 and

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HNF4A

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

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HNF4A. HNF4A

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

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Molecular basis for autosomal-dominant renal Fanconi syndrome caused by HNF4A. Molecular basis for autosomal-dominant renal Fanconi syndrome caused by HNF4A

A specific missense mutation in the DNA binding domain of HNF4A, R85W, causes Fanconi renotubular syndrome (FRTS). To confirm results found in Drosophila, a direct reprogramming approach was applied.

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