Targeted Immunometabolic Intervention for Atherosclerosis Stabilization via PCSK9-Mediated Macrophage Reprogramming

Name: Targeted Immunometabolic Intervention for Atherosclerosis Stabilization via PCSK9-Mediated Macrophage Reprogramming
Creator: The Affiliated Yongchuan Hospital of Chongqing Medical University
Published: 2026-08-18T11:17:16+08:00

integrated proteome resources2026-08-22 收录

动脉粥样硬化

巨噬细胞编程

数据链接：

https://www.iprox.cn/page/project.html?id=IPX0019094000 数据链接链接失效反馈

官方服务：

资源简介：

Targeted Immunometabolic Intervention for Atherosclerosis Stabilization via PCSK9-Mediated Macrophage Reprogramming

提供机构：

The Affiliated Yongchuan Hospital of Chongqing Medical University

创建时间：

2026-08-18

The P2RY12 receptor promotes VSMC-derived foam cell formation by inhibiting autophagy in advanced atherosclerosis

动脉粥样硬化

自噬机制

Vascular smooth muscle cells (VSMCs) are an important source of foam cells in atherosclerosis. The mechanism for VSMC-derived foam cell formation is, however, poorly understood. Here, we demonstrate t

DataCite Commons2024-09-16 更新70

Data_Sheet_3_Tribbles 3 deficiency promotes atherosclerotic fibrous cap thickening and macrophage-mediated extracellular matrix remodelling.xlsx

动脉粥样硬化

生物医学研究

Tribbles 3 (TRIB3) modulates lipid and glucose metabolism, macrophage lipid uptake, with a gain-of-function variant associated with increased cardiovascular risk. Here we set out to examine the role o

frontiersin.figshare.com2023-06-04 更新50

2018年北京小鼠动脉粥样硬化血管组织单细胞测序样本信息

动脉粥样硬化

单细胞测序

本数据集记录了动脉粥样硬化模型小鼠血管组织单细胞测序的样本信息，ApoE-/-经过高脂饮食诱导12周后经过鉴定确定造模成功后，收集模型小鼠的主动脉进行酶解制备单细胞测序所需要的细胞悬液，总共记录了7例样本的信息，其中包括中期和晚期动脉粥样硬化小鼠的血管组织，以及早中晚期动脉粥样硬化相对应的对照血管组织。

国家人口健康科学数据中心20

circRNA expression profiles of mouse atherosclerotic and normal aortae by RNA-seq.. circRNA expression profiles of mouse atherosclerotic and normal aortae by RNA-seq.

动脉粥样硬化

环状RNA表达

To explore circRNAs expression profiles of mouse atherosclerotic model, we performed RNA-seq to detect circRNAs with potential functional role in atherosclerosis (AS). Overall design: CircRNA sequenci

NIAID Data Ecosystem60

Table_1_The effects of pemafibrate and omega-3 fatty acid ethyl on apoB-48 in dyslipidemic patients treated with statin: A prospective, multicenter, open-label, randomized, parallel group trial in Japan (PROUD48 study).docx

血脂异常药物治疗

动脉粥样硬化

BackgroundWe compared the lowering effects of pemafibrate and omega-3 fatty acid ethyl on fasting apolipoprotein (apo) B-48 (apoB-48), a marker that reflects postprandial hypertriglyceridemia, which i

NIAID Data Ecosystem20

Targeted Immunometabolic Intervention for Atherosclerosis Stabilization via PCSK9-Mediated Macrophage Reprogramming

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