It is increasingly appreciated that U1 snRNP transcriptomically suppresses the usage of intronic polyadenylation site (PAS) of mRNAs, an outstanding question is why frequently used PASs are not suppre
In this work, all known and essential protein complexes of the mRNA 3’ processing (CFI, CFII, CstF, mPSF, and the endonuclease complex) were recombinantly expressed and chromatographically purified. F
Crystal structure of the heterodimeric vaccinia virus mRNA polyadenylate polymerase complex with UU and 3'-deoxy ATP Descriptor: 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, 5'-R(UP*U)-3', CALCIUM ION, ... Auth