Centroid calculation for each cluster in Fig. 1. The distance between clusters is represented as a difference of absolute values on the PC1 and PC2 axes. (XLSX 9 kb)
Tabula Muris Senis是一个全面的小鼠衰老细胞图谱数据库,收录了从小鼠整个生命周期中不同器官的单细胞和批量RNA测序数据。该数据库提供了细胞类型特异性的分子和表型特征,用于研究哺乳动物在生命周期内经历的细胞生物学变化。项目包含20个器官的单细胞转录组分析,是理解基因在细胞类型特异性使用方式及其随时间变化的重要资源。
Autism spectrum disorders (ASD) are ~4-times more common in males than females, and CHD8 (a chromatin remodeler)-related ASD shows a strong male bias (~5:1), although the underlying mechanism remains