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Transcriptional profiling of Ishikawa cells treated with H3B-5942, E2, or standard of care compounds

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NIAID Data Ecosystem2026-03-11 收录
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The objective of this experiment was to determine the affect of H3B-5942 treatment on global gene expression in an estrogen-deprived setting (agonist mode) and to compare to treatment with a saturated analog of H3B-5942, GDC-0810, and standard of care agents tamoxifen and fulvestrant. 7 conditions were assessed (H3B-5924, H3B-9224, E2, fulvestrant, tamoxifen, GDC-810, and DMSO as negative control). Compounds were added at 2 concentrations (3nM and 30nM). Two samples of each condition were collected.

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2019-03-21
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