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Metabolic re-programming of pancreatic cancer mediated by CDK4/6 inhibition elicits unique vulnerabilities

ChEBI2015-12-21 更新2026-07-12 收录

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数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-75979 数据链接链接失效反馈

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Metabolic re-programming of pancreatic cancer mediated by CDK4/6 inhibition elicits unique vulnerabilities

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创建时间：

2015-12-21

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RAS信号通路抑制

Crystal structure of BRAF/MEK1 complex with NST-628 and an active RAF dimer Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Dual specificity mitogen-activated protein kinase kina

Protein Data Bank Japan2024-07-10 更新60

Table S2 from Disruption of TFIIH activities generates a stress gene expression response and reveals possible new targets against cancer

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Disruption of the enzymatic activities of the transcription factor TFIIH by the small molecules Triptolide (TPL) or THZ1 could be used against cancer. Here, we used the MCF10A-ErSrc oncogenesis model

Figshare2020-06-01 更新30

Fat graft survival requires metabolic reprogramming towards glycolytic pathway. Fat graft survival requires metabolic reprogramming towards glycolytic pathway

脂肪移植

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Background: The mechanisms underlying fat graft survival are poorly understood. Here, we performed unbiased transcriptomics analysis of mouse fat graft model to find out the molecular mechanism of fre

NIAID Data Ecosystem20

Depletion of Nrf2 in pancreatic cancer cells shifts arginine metabolism into the phosphocreatine energy system. Depletion of Nrf2 in pancreatic cancer cells shifts arginine metabolism into the phosphocreatine energy system

癌细胞重编程

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Depletion of Nrf2 leads to an increase in cellular ROS, reduced glutathione and thiols, and profound reprogramming of metabolism. Unbiased transcriptome analyses show that key enzymes of glycolysis, p

NIAID Data Ecosystem60

Development of Aptamer-DNAzyme Based Metal-Nucleic Acid Frameworks for Gastric Cancer therapy

核酸适配体药物递送

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All data from source data

NIAID Data Ecosystem20