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Genetic and functional analyses of archaeal ATP-dependent RNA Ligase

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NIAID Data Ecosystem2026-03-13 收录
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In this study, we generated allelic knockouts of ATP-dependent RNA ligase (Rnl) in hyperthermophilic archaeon T. kodakarensis and analyze the small RNAs. T. kodakarensis gene encoding for RNA ligase TK1545 was knock-out by homologous recombination, and the RNA samples were analyzed by RNA seq. The differentially expressed circular RNAs between the two strains were analyzed.

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2022-08-04
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