Crystal Structure of BAZ2A bromodomain in complex with acetylindole compound UZH47

Crystal Structure of BAZ2A bromodomain in complex with acetylindole compound UZH47 Descriptor: Bromodomain adjacent to zinc finger domain protein 2A, MAGNESIUM ION, N-(1-acetyl-1H-indol-3-yl)-N-(5-hydroxy-2-methylphenyl)acetamide Authors: Dalle Vedove, A, Unzue, A, Nevado, C, Lolli, G, Caflisch, A. Deposit date: 2018-01-11 Release date: 2018-05-30 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural Analysis of Small-Molecule Binding to the BAZ2A and BAZ2B Bromodomains. ChemMedChem, 13, 2018与乙酰吲哚类化合物UZH47结合的BAZ2A溴结构域（bromodomain）晶体结构 描述：该复合物的组成为锌指结构域邻近蛋白2A（bromodomain adjacent to zinc finger domain protein 2A）、镁离子与N-(1-乙酰基-1H-吲哚-3-基)-N-(5-羟基-2-甲基苯基)乙酰胺 作者：Dalle Vedove, A、Unzue, A、Nevado, C、Lolli, G、Caflisch, A 提交日期：2018-01-11 发布日期：2018-05-30 最后修改日期：2024-01-17 实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.1埃 引用文献：《小分子结合BAZ2A与BAZ2B溴结构域的结构分析》，*ChemMedChem*，第13卷，2018年