Phenotypes of α3 isoform knock-in mouse models.

Figshare2017-05-18 更新2026-04-29 收录

疾病模型

小鼠表型分析

数据链接：

https://figshare.com/articles/dataset/Phenotypes_of_sub_3_sub_isoform_knock-in_mouse_models_/4971107 数据链接链接失效反馈

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资源简介：

Comparison of major phenotypes of α3+/D801Y, Mashlool (α3+/D801N) and Myshkin (α3+/I810N) mice to corresponding RDP and AHC symptoms.

创建时间：

2017-05-18

NOD/ShiLtJGpt-Prf1 em9Cd161 /Gpt

基因功能

疾病模型

Prf1（Perforin1）基因又称Pfn、Pfp，编码穿孔素蛋白。穿孔素（PRF，PRF1）是一种必需的成孔蛋白，由细胞毒性T淋巴细胞（CLs）细胞和CD8+T细胞表达并释放到靶细胞接触的位点，在那里低聚形成靶细胞膜上的孔，允许扩散一系列诱导细胞凋亡的丝氨酸蛋白酶、颗粒酶，进入靶细胞[1-2]。研究表明，穿孔素是参与细胞毒性细胞杀伤靶细胞的一个重要分子，在免疫监视、免疫调控中起着重要作用，其功

中国科技资源共享网2026-02-27 更新310

Whole genome sequencing of Ovol2FSPpcd1 Mouse

基因组测序

疾病模型

The goal was to define the chromosomal rearrangement associated with our mouse model of PPCD1 and confirm a disruption of Ovol2

NIAID Data Ecosystem50

Additional file 2 of Gdaphen, R pipeline to identify the most important qualitative and quantitative predictor variables from phenotypic data

小鼠表型分析

遗传预测变量识别

Additional file 2. Table S2: Input data of Scn10aG1662 mutant mouse line. Each row shows data from one individual and each column all the features quantified and metadata.

Figshare2023-04-13 更新30

Additional file 3 of Developing an experimental necrotic enteritis model in turkeys - the impact of Clostridium perfringens, Eimeria meleagrimitis and host age on frequency of severe intestinal lesions

动物健康

疾病模型

Additional file 3. Data supporting conclusions regarding impact of study variables on OPG counts.

DataCite Commons2020-08-25 更新80

Body composition at 30 weeks of age.

小鼠表型分析

基因功能研究

Body composition assessed by DEXA. Values are presented as group mean ± SEM. Body weight at assessment for WT mice (n = 8): 36.1±1.5 g, Fxr KO mice (n = 8): 28.2±1.4 g. Statistical analysis performed

NIAID Data Ecosystem40

Phenotypes of α3 isoform knock-in mouse models.

资源简介：

相关数据集