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Disruption of dNTPs Homeostasis by Ribonucleotide Reductase Hyperactivation Overcomes AML Differentiation Blockade. Disruption of dNTPs Homeostasis by Ribonucleotide Reductase Hyperactivation Overcomes AML Differentiation Blockade

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NIAID Data Ecosystem2026-03-13 收录
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We assessed global gene expression changes in THP1 cells overexpressing inducible RRM2 non-degradable mutant versus empty vector upon doxycycline induction Overall design: Expression profiling data in THP1 cells transduced with iRxI/AxA mutant (4 replicates) were compared to MOCK control cells (4 replicates) by RNA sequencing

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2022-01-16
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