We assessed global gene expression changes in THP1 cells overexpressing inducible RRM2 non-degradable mutant versus empty vector upon doxycycline induction Overall design: Expression profiling data in
In the present study, we demonstrate that YAP1 is activated by NEDD4-LLPS during mESCs differentiation to ectoderm layers, and that mCINAP determines the differentiation fates of mESCs by regulating N
The histone demethylase LSD1 is deregulated in several tumors, including leukemias, providing the rationale for the clinical use of LSD1 inhibitors. In acute promyelocytic leukemia (APL), pharmacologi
