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Gp130-dependent release of acute phase proteins is linked to the activation of innate immune signaling pathways

ChEBI2010-11-13 更新2026-07-21 收录

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急性期蛋白调控

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-25278 数据链接链接失效反馈

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Gp130-dependent release of acute phase proteins is linked to the activation of innate immune signaling pathways

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2010-11-13

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神经抗病毒免疫

Human herpes simplex virus-1 (HSV-1) encephalitis can be caused by inborn errors of the TLR3 pathway resulting in impairment of central nervous system (CNS) cell-intrinsic antiviral immunity. Deficien

NIAID Data Ecosystem110

Mechanisms Establishing TLR4-Responsive Activation States of Inflammatory Response Genes

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炎症与表观遗传调控

Precise control of the innate immune response is required for resistance to microbial infections and maintenance of normal tissue homeostasis. Because this response involves coordinate regulation of h

NIAID Data Ecosystem60

Figure S1 - Cross-Talk between TLR4 and FcγReceptorIII (CD16) Pathways

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受体串扰机制

Cytokine response of PMNs and macrophages to Zymosan and Pam3Cys. In vitro cytokine responses to non-TLR4 agonists of elicited peritoneal phagocytes from Wt or TLR4 mut mice. PMNs (A–D) and macrophage

NIAID Data Ecosystem40

Crystal structure of human cGAS apo form

蛋白质晶体

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Crystal structure of human cGAS apo form Descriptor: Cyclic GMP-AMP synthase, ZINC ION Authors: Kato, K, Ishii, R, Ishitani, R, Nureki, O. Deposit date: 2013-09-05 Release date: 2013-10-30 Last modifi

Protein Data Bank Japan2023-11-08 更新70

Inherited human IRAK-1 deficiency selectively abolishes TLR signaling in fibroblasts

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免疫表型

We describe here a male infant with a 100 kb de novo Xq28 deletion encompassing parts of the TMEM187 and MECP2 protein-coding genes and the IRAK1 protein-coding gene, as well as the MIR3202-1, MIR3202

NIAID Data Ecosystem50

Gp130-dependent release of acute phase proteins is linked to the activation of innate immune signaling pathways

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