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in vivo evolution of antimicrobial resistance in a mouse model of chronic lung infection

NIAID Data Ecosystem2026-05-01 收录

耐药性进化

肺部感染模型

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP471990 数据链接链接失效反馈

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资源简介：

This project is studying the evolution of biofilm antimicrobial resistance in a chronic lung infection of BALB/c mice using Pseudomonas aeruginosa.

应用场景：

创建时间：

2023-11-18

耐药性进化

葡萄球菌基因组

Several lines of evidence indicate that the most primitive staphylococcal species, the Staphylococcus sciuri group, were involved in the first stages of evolution of SCCmec – the genetic element carry

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Assemblies (zipped directory)

细菌基因组学

耐药性进化

1092 Klebsiella pneumoniae genome assemblies. These data are described in Wyres et al "Distinct evolutionary dynamics of horizontal gene transfer in drug resistant and virulent clones of Klebsiella pn

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Evolutionary outcomes of plasmid-CRISPR conflicts in an opportunistic pathogen

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CRISPR-质粒冲突

The persistence of antibiotic resistance plasmids in pathogens is a global health concern. Plasmid persistence results from host-plasmid co-evolution that enhances plasmid stability, where the role of

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Experimental evolution of high levels antibiotic resistance and collateral sensitivity in Pseudomonas aeruginosa. Pseudomonas aeruginosa PA14

耐药性进化

附带敏感性

We aimed at using experimental evolution to elucidate the mechanisms of high-level antibiotic resistance evolution and the possibility of collateral effects. As a model we used the opportunistic patho

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The_genome_sequence_of_Salmonella_Typhimurium_strain_RS9H8. The_genome_sequence_of_Salmonella_Typhimurium_strain_RS9H8

细菌基因组学

耐药性进化

We will generate whole genome sequence of a representative isolate of this epidemic group in order to determine its phylogenetic relationship and microevolutionary features that are in common or disti

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in vivo evolution of antimicrobial resistance in a mouse model of chronic lung infection

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