Effect of COPI depletion on senescence model systems. Effect of COPI depletion on senescence model systems
收藏NIAID Data Ecosystem2026-03-14 收录
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To examine effects of COPI depletion on senescence transcriptional signatures we generated cell lines (IMR90 or IMR90 ER:RAS cells) with inducible 2 COPI shRNAs or control shRNAs and induced to senesce with either treatment with Bleomycin or 4OHT treatment. Transcriptional analysis was performed 3 days after induction of doxycycline inducible harpins and 10 days after senescence induction. Overall design: Comparative gene expression profiling analysis of RNA-seq data for IMR90/IMR90 ER:RAS cells and its KD derivatives (shRNA Control, shCOPB2_1, shCOPB2_2).
创建时间：
2023-01-30
